Treatment of Shock and Prevention of Ischemic Necrosis with Levarterenol-Phentolamine Mixtures

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Treatment of shock and prevention of ischemic necrosis with levarterenol-phentolamine mixtures.

ISCHEMIC NECROSIS resultinig from accidental extravasation of levarterenol (Levophed) in patients in shock can be prevented by local injection of 5 or 10 mg. of the anti-adrenergic drug phentolamine (Regitine).'4 This method is not effective when vasoconstriction has existed for several hours and irreversible tissue damage has occurred. Preliminary observatioins suggest that inmediate protectio...

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ژورنال

عنوان ژورنال: Circulation

سال: 1960

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.22.5.935